Annual report pursuant to Section 13 and 15(d)

Fair Value Measurements - Narrative (Details)

v3.23.1
Fair Value Measurements - Narrative (Details)
$ in Thousands
 12 Months Ended
Nov. 07, 2022
USD ($)
Dec. 31, 2022
USD ($)
Derivative Financial Instruments, Liabilities    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability   $ 4,830
AVTX-501 And AVTX-007 | Derivative Financial Instruments, Liabilities    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability $ 4,800  
AVTX-501    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment 20,000  
AVTX-501 | Derivative Financial Instruments, Liabilities    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability $ 3,500  
AVTX-501 | Derivative Financial Instruments, Liabilities | Measurement Input, Probability Of Success    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input 0.23  
AVTX-501 | Derivative Financial Instruments, Liabilities | Measurement Input, Expected Term    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative Liability, Measurement Input, Term 5 years  
AVTX-007 | Derivative Financial Instruments, Liabilities    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability $ 1,300  
AVTX-007 | Derivative Financial Instruments, Liabilities | Measurement Input, Probability Of Success    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input 0.17  
AVTX-007 | Derivative Financial Instruments, Liabilities | Measurement Input, Expected Term    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative Liability, Measurement Input, Term 6 years  
AVTX-007 | Derivative Financial Instruments, Liabilities | Measurement Input, Sales Forecast Peak    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input 300,000  
AVTX-611    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment $ 20,000  
ES | Derivative Financial Instruments, Liabilities    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability 5,000  
Milestone One | AVTX-007    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment 6,250  
Milestone Two | AVTX-007    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment $ 67,500