Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies (Details)

v3.24.1
Commitments and Contingencies (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Mar. 27, 2024
USD ($)
Oct. 27, 2023
USD ($)
Feb. 03, 2020
USD ($)
milestone
Sep. 24, 2018
USD ($)
therapy
milestone
Jul. 31, 2019
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2019
unit
$ / shares
Aug. 14, 2023
USD ($)
Jun. 22, 2021
USD ($)
Jun. 09, 2021
USD ($)
May 28, 2021
USD ($)
Mar. 25, 2021
USD ($)
Loss Contingencies [Line Items]                          
Accrued expenses and other current liabilities           $ 4,172 $ 13,214            
Total revenues, net           1,924 18,051            
Royalty agreement, payment received         $ 2,000                
Period after public launch to terminate agreement         3 years                
Buyout option, percentage of net present value of royalty payments         75.00%                
Aevi                          
Loss Contingencies [Line Items]                          
Payment for contingent consideration           0              
Aevi                          
Loss Contingencies [Line Items]                          
Number of contingent consideration milestones | milestone     2                    
Contingent consideration     $ 6,500                    
Ichorion                          
Loss Contingencies [Line Items]                          
Contingent consideration       $ 15,000                  
Payment for contingent consideration           0              
Number of contingent consideration milestones | milestone       3                  
AlmataBio Transaction | Subsequent Event                          
Loss Contingencies [Line Items]                          
Payment to acquire business $ 7,500                        
License and other revenue                          
Loss Contingencies [Line Items]                          
Total revenues, net           516 14,687            
CERC-801, CERC-802, And CERC-803 | Ichorion                          
Loss Contingencies [Line Items]                          
Number of preclinical therapies | therapy       3                  
CERC-913 | Ichorion                          
Loss Contingencies [Line Items]                          
Number of preclinical therapies | therapy       1                  
Milestone One | Aevi                          
Loss Contingencies [Line Items]                          
Contingent consideration     2,000                    
Milestone One | Ichorion                          
Loss Contingencies [Line Items]                          
Payment for contingent consideration       $ 6,000                  
Milestone One | AlmataBio Transaction | Subsequent Event                          
Loss Contingencies [Line Items]                          
Contingent consideration 5,000                        
Milestone Two | Aevi                          
Loss Contingencies [Line Items]                          
Contingent consideration     $ 4,500                    
Milestone Two | Ichorion                          
Loss Contingencies [Line Items]                          
Payment for contingent consideration       5,000                  
Milestone Two | AlmataBio Transaction | Subsequent Event                          
Loss Contingencies [Line Items]                          
Contingent consideration $ 15,000                        
Milestone Three | Ichorion                          
Loss Contingencies [Line Items]                          
Payment for contingent consideration       $ 4,000     0            
Lilly License Agreement | AVTX-009 Lilly License Agreement                          
Loss Contingencies [Line Items]                          
Collaborative arrangement, rights and obligations, milestone payments           70,000              
Lilly License Agreement | AVTX-009 Lilly License Agreement | Milestone One                          
Loss Contingencies [Line Items]                          
Maximum aggregate milestone payment           720,000              
Kyowa Kirin Co., Ltd. (KKC) | AVTX-002 KKC License Agreement                          
Loss Contingencies [Line Items]                          
Upfront license fee                         $ 10,000
Percent of payments received from sublicensing                         30.00%
Research and development           0              
Cumulative expense recognized to date           0              
Kyowa Kirin Co., Ltd. (KKC) | AVTX-002 KKC License Agreement | Milestone One                          
Loss Contingencies [Line Items]                          
Maximum aggregate milestone payment                         $ 112,500
Kyowa Kirin Co., Ltd. (KKC) | AVTX-002 KKC License Agreement | Milestone Two                          
Loss Contingencies [Line Items]                          
Maximum aggregate milestone payment                         $ 75,000
Sanford Burnham Prebys Medical Discovery Institute | AVTX-008 Sanford Burnham Prebys License Agreement                          
Loss Contingencies [Line Items]                          
Upfront license fee                   $ 400      
Research and development           0              
Patent costs                   500      
Cumulative expense recognized to date           0              
Sanford Burnham Prebys Medical Discovery Institute | AVTX-008 Sanford Burnham Prebys License Agreement | Milestone One                          
Loss Contingencies [Line Items]                          
Maximum aggregate milestone payment                   24,200      
Sanford Burnham Prebys Medical Discovery Institute | AVTX-008 Sanford Burnham Prebys License Agreement | Milestone Two                          
Loss Contingencies [Line Items]                          
Maximum aggregate milestone payment                   $ 50,000      
Astellas Pharma, Inc. (Astellas) | AVTX-006 Astellas License Agreement                          
Loss Contingencies [Line Items]                          
Maximum aggregate milestone payment           5,500              
Upfront license fee           500              
Research and development           0              
Cumulative expense recognized to date           500              
Alto | AVTX-301 Out-License                          
Loss Contingencies [Line Items]                          
Maximum proceeds from milestones                       $ 18,600  
Revenue recognized from milestones to date             0            
ES | AVTX-406 License Assignment                          
Loss Contingencies [Line Items]                          
Revenue recognized from milestones to date             $ 0            
ES | Milestone One | AVTX-406 License Assignment                          
Loss Contingencies [Line Items]                          
Maximum proceeds from milestones                     $ 6,000    
ES | Milestone Two | AVTX-406 License Assignment                          
Loss Contingencies [Line Items]                          
Maximum proceeds from milestones                     $ 20,000    
AUG Therapeutics, LLC | Purchase Agreement                          
Loss Contingencies [Line Items]                          
Upfront payment paid   $ 200                      
Asset acquisition consideration transferred, liabilities   $ 400                      
Contingent milestone upfront payment percentage   0.20                      
Contingent milestone payment   $ 15,000                      
Maximum potential payments   45,000                      
AUG Therapeutics, LLC | Purchase Agreement | AVTX-800 Series Asset Sale                          
Loss Contingencies [Line Items]                          
Upfront payment paid   200                      
Asset acquisition consideration transferred, liabilities   $ 400                      
Contingent milestone upfront payment percentage   0.20                      
Contingent milestone payment   $ 15,000                      
Maximum potential payments   $ 45,000                      
AUG Therapeutics, LLC | Purchase Agreement | License and other revenue                          
Loss Contingencies [Line Items]                          
Total revenues, net           500              
TRIS Pharma | Karbinal Agreement                          
Loss Contingencies [Line Items]                          
Minimum quantity required | unit               70,000          
Make whole payment per unit (in dollars per share) | $ / shares               $ 30          
Apollo AP43 Limited                          
Loss Contingencies [Line Items]                          
Estimate of possible loss                 $ 800        
Accrued expenses and other current liabilities           $ 200