Annual report pursuant to Section 13 and 15(d)

Fair Value Measurements - Narrative (Details)

v3.24.1
Fair Value Measurements - Narrative (Details)
$ in Thousands
12 Months Ended
Nov. 07, 2022
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Goodwill impairment   $ 3,907 $ 0
Change in fair value of derivative liability   720 0
Derivative Financial Instruments, Liabilities      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent consideration   5,550 $ 4,830
AVTX-501 And AVTX-007 | Derivative Financial Instruments, Liabilities      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Fair value, measurement with unobservable inputs reconciliation, recurring basis, liability, issuances $ 4,800 5,600  
AVTX-501      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment 20,000    
AVTX-501 | Derivative Financial Instruments, Liabilities      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Fair value, measurement with unobservable inputs reconciliation, recurring basis, liability, issuances $ 3,500 3,800  
AVTX-501 | Derivative Financial Instruments, Liabilities | Measurement Input, Probability Of Success      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input 0.23    
AVTX-501 | Derivative Financial Instruments, Liabilities | Measurement Input, Expected Term      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input term 3 years 9 months 18 days    
AVTX-007 | Derivative Financial Instruments, Liabilities      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Fair value, measurement with unobservable inputs reconciliation, recurring basis, liability, issuances $ 1,300 $ 1,700  
AVTX-007 | Derivative Financial Instruments, Liabilities | Measurement Input, Probability Of Success      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input 0.17    
AVTX-007 | Derivative Financial Instruments, Liabilities | Measurement Input, Expected Term      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input term 4 years 9 months 18 days    
AVTX-007 | Derivative Financial Instruments, Liabilities | Measurement Input, Sales Forecast Peak      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input 300,000    
AVTX-611      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment $ 20,000    
ES | Derivative Financial Instruments, Liabilities      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Fair value, measurement with unobservable inputs reconciliation, recurring basis, liability, issuances 5,000    
Milestone One | AVTX-007      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment 6,250    
Milestone Two | AVTX-007      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment $ 67,500