Quarterly report pursuant to Section 13 or 15(d)

Subsequent Events - Proforma Summary Balance Sheet Data Adjustments for Janssen Purchase Agreement (Details)

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Subsequent Events - Proforma Summary Balance Sheet Data Adjustments for Janssen Purchase Agreement (Details) - USD ($)
 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Subsequent Event [Line Items]        
Increase in cash $ 332,741 $ (9,282,422)    
Cash and cash equivalents 5,460,699 $ 11,879,545 $ 5,127,958 $ 21,161,967
Total assets 6,047,731   5,768,865  
Total liabilities 2,912,236   5,561,863  
Preferred stock 4   0  
Common stock 14,115   9,434  
Additional paid in capital 76,915,611   70,232,651  
Accumulated deficit 73,794,235   70,035,083  
Total stockholders’ equity 3,135,495   $ 207,002  
Actual        
Subsequent Event [Line Items]        
Escrow funds from the sale of asset 0      
Cash and cash equivalents 5,460,699      
Total assets 6,047,731      
Total liabilities 2,912,236      
Preferred stock 4      
Common stock 14,115      
Additional paid in capital 76,915,611      
Accumulated deficit 73,794,235      
Total stockholders’ equity 3,135,495      
Pro forma        
Subsequent Event [Line Items]        
Increase in cash 21,250,000      
Escrow funds from the sale of asset 3,750,000      
Closing costs 125,000      
Reduction in accumulated deficit 24,875,000      
Cash and cash equivalents 26,710,699      
Total assets 31,047,731      
Total liabilities 3,037,236      
Preferred stock 4      
Common stock 14,115      
Additional paid in capital 76,915,611      
Accumulated deficit 48,919,235      
Total stockholders’ equity $ 28,010,495