Quarterly report pursuant to Section 13 or 15(d)

Fair Value Measurements - Narrative (Details)

v3.23.2
Fair Value Measurements - Narrative (Details)
$ in Thousands
 3 Months Ended 6 Months Ended
Mar. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Jun. 30, 2023
USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Change in fair value was recognized     $ 200
Significant other observable inputs (Level 2)      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Estimated fair value of debt     10,000
AVTX-501      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment   $ 20,000  
AVTX-611      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment   20,000  
Milestone One | AVTX-007      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment   6,250  
Milestone Two | AVTX-007      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Maximum aggregate milestone payment   67,500  
Derivative liability | AVTX-501 And AVTX-007      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Initial valuation of derivative liability   4,800 5,100
Derivative liability | AVTX-501      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Initial valuation of derivative liability $ 3,500   $ 3,700
Derivative liability | AVTX-501 | Measurement Input, Probability Of Success      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input     0.23
Derivative liability | AVTX-501 | Measurement Input, Expected Term      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input, term     4 years 3 months 18 days
Derivative liability | AVTX-007      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Initial valuation of derivative liability $ 1,300   $ 1,300
Derivative liability | AVTX-007 | Measurement Input, Probability Of Success      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input     0.17
Derivative liability | AVTX-007 | Measurement Input, Expected Term      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input, term     5 years 3 months 18 days
Derivative liability | AVTX-007 | Measurement Input, Sales Forecast Peak      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative liability, measurement input     300,000
ES | Derivative liability      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Initial valuation of derivative liability   $ 5,000