Quarterly report pursuant to Section 13 or 15(d)

Fair Value Measurements - Narrative (Details)

v3.23.1
Fair Value Measurements - Narrative (Details)
$ in Thousands
3 Months Ended
Mar. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Change in fair value was recognized $ 200  
AVTX-501    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment   $ 20,000
AVTX-611    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment   20,000
Milestone One | AVTX-007    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment   6,250
Milestone Two | AVTX-007    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Maximum aggregate milestone payment   67,500
Derivative liability | AVTX-501 And AVTX-007    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability 5,000 4,800
Derivative liability | AVTX-501    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability $ 3,800 3,500
Derivative liability | AVTX-501 | Measurement Input, Probability Of Success    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input 0.23  
Derivative liability | AVTX-501 | Measurement Input, Expected Term    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input, term 4 years 7 months 6 days  
Derivative liability | AVTX-007    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability $ 1,300 1,300
Derivative liability | AVTX-007 | Measurement Input, Probability Of Success    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input 0.17  
Derivative liability | AVTX-007 | Measurement Input, Expected Term    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input, term 5 years 7 months 6 days  
Derivative liability | AVTX-007 | Measurement Input, Sales Forecast Peak    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Derivative liability, measurement input 300,000  
ES | Derivative liability    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Initial valuation of derivative liability   $ 5,000