Quarterly report pursuant to Section 13 or 15(d)

Common Stock and Stock Based Compensation (Details)

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Common Stock and Stock Based Compensation (Details)
 9 Months Ended 12 Months Ended
Sep. 01, 2015
$ / shares
May. 08, 2012
item
$ / shares
shares
Sep. 30, 2015
USD ($)
item
$ / shares
shares
Sep. 30, 2014
USD ($)
Dec. 31, 2014
$ / shares
shares
May. 07, 2013
shares
Jan. 11, 2012
shares
Aug. 28, 2011
shares
Common stock, Par value | $ / shares $ 0.001   $ 0.001   $ 0.001      
Number of votes per share | item     1          
Total stock-based compensation     $ 321,228 $ 917,996        
Number of shares                
Balance, December 31, 2014 | shares     552,726          
Granted | shares     72,856          
Forfeitures | shares     (114,698)          
Balance, September 30, 2015 | shares     510,884   552,726      
Vested or expected to vest | shares     510,884          
Exercisable | shares     439,607          
Weighted-average exercise price                
Balance, December 31, 2014 | $ / shares     $ 9.17          
Granted | $ / shares     6.22          
Forfeitures | $ / shares     8.59          
Balance, September 30, 2015 | $ / shares     8.88   $ 9.17      
Vested or expected to vest | $ / shares     8.88          
Exercisable | $ / shares     $ 9.26          
Fair value of options granted                
Granted     $ 211,262          
Weighted-average remaining contractual term (in years)                
Balance     7 years 4 months 21 days   8 years 2 months 1 day      
Vested or expected to vest     7 years 4 months 21 days          
Exercisable     7 years 6 months 15 days          
2015     $ 19,095          
2016     57,419          
2017     45,932          
2018     42,495          
2019     14,113          
Total unrecognized compensation expense     179,054          
Research and development expense                
Total stock-based compensation     57,353 181,256        
General and administrative                
Total stock-based compensation     $ 263,875 $ 736,740        
2011 stock incentive plan                
Number of shares authorized for issuance | shares           704,428 285,714 178,571
Options term (in years)     10 years          
Number of common stock remaining for future issuance (in shares) | shares   167,857 254,236          
2011 stock incentive plan | Minimum                
Vesting period     3 years          
2011 stock incentive plan | Maximum                
Vesting period     4 years          
Outside of Plan                
Number of grants outside of the Plan | shares   3            
Number of non-employee directors granted stock options | item   2            
Percentage of vesting   33.00%            
Number of consecutive annual anniversaries for vesting | item   3            
Number of shares                
Granted | shares   167,857            
Weighted-average exercise price                
Granted | $ / shares   $ 8.68            
Common stock                
Reverse stock split ratio 0.03571