Quarterly report pursuant to Section 13 or 15(d)

Condensed Consolidated Statements of Changes in Stockholder's Equity (Unaudited)

Condensed Consolidated Statements of Changes in Stockholder's Equity (Unaudited) - USD ($)	Total	Common stock	Preferred Stock	Additional paid in capital	Contingently issuable stock	Accumulated deficit
Balance at the beginning (in shares) at Dec. 31, 2017		31,266,989	0
Balance at the beginning at Dec. 31, 2017	$ 27,859,608	$ 31,268	$ 0	$ 83,338,136	$ 2,655,464	$ (58,165,260)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock (in shares)		2,349,968
Issuance of stock	0	$ 2,350		2,653,114	(2,655,464)
Exercise of stock options and warrants (in shares)		153,729
Exercise of stock options and warrants	390,473	$ 154		390,319
Shares purchased through employee stock purchase plan (in shares)		20,000
Shares purchased through employee stock purchase plan	8,400	$ 20		8,380
Stock-based compensation	851,255			851,255
Net loss	(9,890,319)					(9,890,319)
Balance at the end (in shares) at Jun. 30, 2018		33,790,686	0
Balance at the end at Jun. 30, 2018	19,219,417	$ 33,792	$ 0	87,241,204	0	(68,055,579)
Balance at the beginning (in shares) at Mar. 31, 2018		31,410,335	0
Balance at the beginning at Mar. 31, 2018	24,582,980	$ 31,411	$ 0	83,944,208	2,655,464	(62,048,103)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock (in shares)		2,349,968
Issuance of stock	0	$ 2,350		2,653,114	(2,655,464)
Exercise of stock options and warrants (in shares)		10,383
Exercise of stock options and warrants	27,082	$ 11		27,071
Shares purchased through employee stock purchase plan (in shares)		20,000
Shares purchased through employee stock purchase plan	8,400	$ 20		8,380
Stock-based compensation	608,431			608,431
Net loss	(6,007,476)					(6,007,476)
Balance at the end (in shares) at Jun. 30, 2018		33,790,686	0
Balance at the end at Jun. 30, 2018	19,219,417	$ 33,792	$ 0	87,241,204	0	(68,055,579)
Balance at the beginning (in shares) at Dec. 31, 2018		40,804,189	2,857,143
Balance at the beginning at Dec. 31, 2018	20,907,748	$ 40,804	$ 2,857	119,082,157	0	(98,218,070)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock (in shares)		1,818,182
Issuance of stock	8,975,960	$ 1,818		8,974,142
Exercise of stock options and warrants (in shares)		74,413
Exercise of stock options and warrants	$ 256,816	$ 74		256,742
Restricted Stock Units vested during period (in shares)	161,250
Restricted Stock Units vested during period	$ 0	162		(162)
Restricted Stock Units withheld for taxes (in shares)	(3,723)
Restricted Stock Units withheld for taxes	$ (18,057)	$ (4)		(18,053)
Shares purchased through employee stock purchase plan (in shares)		43,940
Shares purchased through employee stock purchase plan	127,537	$ 44		127,493
Stock-based compensation	1,123,402			1,123,402
Net loss	(13,677,147)					(13,677,147)
Balance at the end (in shares) at Jun. 30, 2019		42,898,251	2,857,143
Balance at the end at Jun. 30, 2019	17,696,259	$ 42,898	$ 2,857	129,545,721	0	(111,895,217)
Balance at the beginning (in shares) at Mar. 31, 2019		42,753,659	2,857,143
Balance at the beginning at Mar. 31, 2019	23,120,530	$ 42,754	$ 2,857	128,747,037	0	(105,672,118)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Exercise of stock options and warrants (in shares)		43,125
Exercise of stock options and warrants	$ 162,639	$ 43		162,596
Restricted Stock Units vested during period (in shares)	61,250
Restricted Stock Units vested during period	$ 0	61		(61)
Restricted Stock Units withheld for taxes (in shares)	(3,723)
Restricted Stock Units withheld for taxes	$ (18,057)	$ (4)		(18,053)
Shares purchased through employee stock purchase plan (in shares)		43,940
Shares purchased through employee stock purchase plan	127,537	$ 44		127,493
Stock-based compensation	526,709			526,709
Net loss	(6,223,099)					(6,223,099)
Balance at the end (in shares) at Jun. 30, 2019		42,898,251	2,857,143
Balance at the end at Jun. 30, 2019	$ 17,696,259	$ 42,898	$ 2,857	$ 129,545,721	$ 0	$ (111,895,217)