Annual report pursuant to Section 13 and 15(d)

Capital Structure - Narrative (Details)

Capital Structure - Narrative (Details)								3 Months Ended		12 Months Ended
Capital Structure - Narrative (Details)	Mar. 08, 2019 USD ($) $ / shares shares	Mar. 05, 2019 USD ($) $ / shares shares	Dec. 27, 2018 USD ($) $ / shares shares	Sep. 24, 2018 $ / shares shares	Aug. 17, 2018 USD ($) $ / shares shares	Nov. 17, 2017 USD ($) shares	Apr. 27, 2017 USD ($) $ / shares shares	Dec. 31, 2018 USD ($) $ / shares shares	Sep. 30, 2018 USD ($) shares	Dec. 31, 2018 USD ($) class_of_stock Vote $ / shares shares	Dec. 31, 2017 USD ($) $ / shares shares	Oct. 31, 2015 shares	Oct. 20, 2015 class_of_stock	Dec. 31, 2014 shares
Capital Structure
Number of classes of stock authorized to issue \| class_of_stock													2
Number of shares of capital stock authorized to issue (in shares)								205,000,000		205,000,000
Common stock, shares authorized (in shares)								200,000,000		200,000,000	200,000,000
Preferred stock, shares authorized (in shares)								5,000,000		5,000,000	5,000,000
Common stock, par value (in dollars per share) \| $ / shares				$ 0.001	$ 0.001			$ 0.001		$ 0.001	$ 0.001
Preferred stock, par value per share (in dollars per share) \| $ / shares								$ 0.001		$ 0.001	$ 0.001
Proceeds from issuance of Series B convertible preferred stock upon warrant exercise, net \| $										$ 5,685,038	$ 0
Deemed distribution to shareholder \| $											0
Gross proceeds \| $										$ 0	$ 1,502,593
Common stock
Capital Structure
Number of shares available under warrant (in shares)												22,328
Issuance of stock (in shares)										2,349,968	2,301,598
Gross proceeds \| $										$ 2,350	$ 2,302
Common Stock
Capital Structure
Number of shares available under warrant (in shares)								4,024,708		4,024,708
Number of votes per share \| Vote										1
Number of preemptive, conversion or subscription rights \| class_of_stock										0
Number of redemption or sinking fund provisions \| class_of_stock										0
Series B convertible preferred stock \| Preferred Stock
Capital Structure
Preferred stock conversion ratio			5							5
Number of shares available under warrant (in shares)														625,208
Private Placement
Capital Structure
Number of shares available under warrant (in shares)											14,285,714
Exercise price per share (in dollars per share) \| $ / shares											$ 0.40
Proceeds from issuance of Series B convertible preferred stock upon warrant exercise, net \| $								$ 5,700,000
Sale of stock price per share (in dollars per share) \| $ / shares					$ 3.91
Proceeds from issuance or sale of equity \| $					$ 3,900,000		$ 4,650,000		$ 3,900,000
Gross proceeds \| $							$ 5,000,000
Convertible preferred stock conversion price (in dollars per share) \| $ / shares							$ 0.35
Private Placement \| Common stock
Capital Structure
Issuance of stock (in shares)					1,000,000		2,345,714		1,000,000
Percentage of outstanding shares issued							19.99%
Convertible preferred stock shares authorized (in shares)							11,940,000
Private Placement \| Series A Preferred Stock \| Preferred Stock
Capital Structure
Preferred stock, shares authorized (in shares)							4,179
Preferred stock, par value per share (in dollars per share) \| $ / shares							$ 1,000
Private Placement \| Series B convertible preferred stock \| Preferred Stock
Capital Structure
Preferred stock, shares authorized (in shares)			2,857,143
Preferred stock, par value per share (in dollars per share) \| $ / shares			$ 2.00
TRx
Capital Structure
Unregistered shares of common stock issued or issuable as part of acquisition \| $						$ 8,100,000
Shares issued upon closing (in shares)						5,184,920
Contingent shares issuable as part of acquisition (in shares)						2,349,968
Ichorion
Capital Structure
Issuance of shares in acquistion (in shares)				5,800,000
Subsequent Event \| Bought Deal
Capital Structure
Sale of stock price per share (in dollars per share) \| $ / shares	$ 5.50	$ 5.50
Number of shares issued (in shares)	1,818,182	1,818,182
Consideration received \| $	$ 9,000,000	$ 9,000,000
Incentive Warrants
Capital Structure
Number of shares available under warrant (in shares)			4,000,000
Exercise price per share (in dollars per share) \| $ / shares			$ 12.50
Expected life			5 years 6 months
Deemed distribution to shareholder \| $			$ 1,657,383							$ 1,700,000
Fair value of warrants \| $			2,200,000
Value forwent by Armistice \| $			$ 500,000
Incentive Warrants \| Measurement input discount rate
Capital Structure
Warrants and rights outstanding measurement input			0.55
Incentive Warrants \| Measurement input risk free interest rate
Capital Structure
Warrants and rights outstanding measurement input			0.0262
Incentive Warrants \| Measurement input strike price (in dollars per share)
Capital Structure
Warrants and rights outstanding measurement input \| $ / shares			12.50
Incentive Warrants \| Measurement input fair value of underlying equity (per share)
Capital Structure
Warrants and rights outstanding measurement input \| $ / shares			3.02
Armistice \| Subsequent Event \| Bought Deal
Capital Structure
Number of shares issued (in shares)	363,637	363,637