Quarterly report pursuant to Section 13 or 15(d)

Capital Structure - Common Stock (Details)

Capital Structure - Common Stock (Details)				3 Months Ended		12 Months Ended
Capital Structure - Common Stock (Details)	Nov. 17, 2017 USD ($) shares	Apr. 27, 2017 USD ($) $ / shares shares	Sep. 08, 2016 USD ($) $ / shares shares	Mar. 31, 2018 USD ($) Vote class_of_stock $ / shares shares	Mar. 31, 2017 USD ($)	Jan. 16, 2018 USD ($) shares	Dec. 31, 2017 USD ($) $ / shares shares	Dec. 31, 2016 USD ($)	Jul. 06, 2017 shares	Jan. 27, 2017 USD ($)	Oct. 20, 2015 class_of_stock
Common Stock
Number of classes of stock authorized to issue \| class_of_stock											2
Number of shares of capital stock authorized to issue (in shares)				205,000,000
Common stock, shares authorized (in shares)				200,000,000			200,000,000
Preferred stock, shares authorized (in shares)				5,000,000			5,000,000
Common stock, par value (in dollars per share) \| $ / shares				$ 0.001			$ 0.001
Preferred stock, par value per share (in dollars per share) \| $ / shares				$ 0.001			$ 0.001
Threshold price per common stock on any trading day to present notice for purchase of common stock (in dollars per share) \| $ / shares			$ 0.50
Number of shares sold under purchase agreement (in shares)				31,410,335			31,266,989
Proceeds from issuance of common stock \| $				$ 0	$ 1,186,564
Aspire Capital Fund LLC (Aspire Capital)
Common Stock
Term of common stock purchase agreement			30 months
Common stock issued as commitment fee (in shares)			175,000
Common Stock
Common Stock
Number of shares available under warrant (in shares)				18,986,659
Number of votes per share \| Vote				1
Number of preemptive, conversion or subscription rights \| class_of_stock				0
Number of redemption or sinking fund provisions \| class_of_stock				0
Private Placement
Common Stock
Convertible preferred stock conversion price (in dollars per share) \| $ / shares		$ 0.35
Gross proceeds \| $		$ 5,000,000
Proceeds from issuance or sale of equity \| $		$ 4,650,000
Number of shares available under warrant (in shares)		14,285,714
Exercise price per share (in dollars per share) \| $ / shares		$ 0.40
Private Placement \| Common stock
Common Stock
Convertible preferred stock shares authorized (in shares)		11,940,000							11,940,000
Issuance of stock (in shares)		2,345,714
Percentage of outstanding shares issued		19.99%
Private Placement \| Series A Preferred Stock \| Preferred Stock
Common Stock
Preferred stock, shares authorized (in shares)		4,179
Preferred stock, par value per share (in dollars per share) \| $ / shares		$ 1,000
Common Stock Purchase Agreement \| Aspire Capital Fund LLC (Aspire Capital)
Common Stock
Maximum value of common stock purchases committed to by counterparty \| $			$ 15,000,000
Number of shares sold under purchase agreement (in shares)			250,000				965,165
Price per share (in dollars per share) \| $ / shares			$ 4.00
Gross proceeds \| $			$ 1,000,000				$ 789,000
Proceeds from issuance of common stock \| $								$ 1,900,000
Common Stock Purchase Agreement \| Maximum \| Aspire Capital Fund LLC (Aspire Capital)
Common Stock
Number of common stock issued per day on achieving threshold price per common stock (in shares)			50,000
Equity Distribution Agreement for Sale of Common Stock \| Maxim Group LLC (Maxim)
Common Stock
Proceeds from issuance of common stock \| $						$ 905,000
Sale of common stock through equity distribution agreement \| $										$ 12,075,338
Payments of stock issuance costs \| $						$ 33,000
Equity Distribution Agreement for Sale of Common Stock \| Maxim Group LLC (Maxim) \| Common stock
Common Stock
Issuance of stock (in shares)						1,336,433
TRx
Common Stock
Unregistered shares of common stock issued or issuable as part of acquisition \| $	$ 8,100,000
Shares issued upon closing (in shares)	5,184,920
Contingent shares issuable as part of acquisition (in shares)	2,349,968