Selected Quarterly Financial Data (Unaudited) (Details) - USD ($) |
3 Months Ended | 12 Months Ended | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Dec. 31, 2016 |
Sep. 30, 2016 |
Jun. 30, 2016 |
Mar. 31, 2016 |
Dec. 31, 2015 |
Sep. 30, 2015 |
Jun. 30, 2015 |
Mar. 31, 2015 |
Dec. 31, 2016 |
Dec. 31, 2015 |
Dec. 31, 2014 |
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| Quarterly Financial Data [Abstract] | |||||||||||
| Grant revenue | $ 182,000 | $ 321,000 | $ 650,000 | $ 0 | $ 1,152,987 | $ 0 | $ 0 | ||||
| Research and development | 773,000 | 4,582,000 | 2,502,000 | 2,293,000 | $ 1,751,000 | $ 1,238,000 | $ 1,875,000 | $ 1,723,000 | 10,149,879 | 6,587,183 | 12,240,535 |
| General and administrative | 1,095,000 | 1,703,000 | 1,636,000 | 2,649,000 | 1,924,000 | 722,000 | 1,016,000 | 761,000 | 7,083,155 | 4,422,764 | 4,875,030 |
| Change in fair value of warrant liability, unit purchase option liability and investor rights obligation | 130,000 | (101,000) | 91,000 | (47,000) | 185,000 | 1,465,000 | 198,000 | (535,000) | 72,625 | 1,313,049 | 2,266,161 |
| Interest income (expense), net | (83,000) | (104,000) | (127,000) | (151,000) | (158,000) | (197,000) | (219,000) | (219,000) | (464,181) | (793,205) | (1,206,187) |
| Net loss | $ (1,639,000) | $ (6,169,000) | $ (3,524,000) | $ (5,140,000) | $ (3,648,000) | $ (692,000) | $ (2,912,000) | $ (3,238,000) | $ (16,471,603) | $ (10,490,103) | $ (16,055,591) |
| Net loss per share of common stock, basic and diluted | $ (0.18) | $ (0.70) | $ (0.41) | $ (0.59) | $ (0.53) | $ (1.06) | $ (4.48) | $ (4.98) | $ (1.87) | $ (4.71) | $ (5.48) |
| X | ||||||||||
- Definition Amount of expense (income) related to adjustment to fair value of warrant liability and investor rights obligation. No definition available.
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- Definition The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period. No definition available.
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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The net amount of nonoperating interest income (expense). No definition available.
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- References No definition available.
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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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