Quarterly report pursuant to Section 13 or 15(d)

Fair Value Measurements - Narrative (Details)

v3.24.2
Fair Value Measurements - Narrative (Details)
$ in Thousands
 3 Months Ended
Mar. 28, 2024
USD ($)
shares
Mar. 31, 2024
USD ($)
Mar. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Net proceeds from the sale $ 79,300 $ 79,276 $ 0  
Change in fair value of derivative liability   120 $ 180  
AVTX-501        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Maximum aggregate milestone payment       $ 20,000
AVTX-007 | Milestone One        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Maximum aggregate milestone payment       6,250
AVTX-007 | Milestone Two        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Maximum aggregate milestone payment       67,500
AVTX-611        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Maximum aggregate milestone payment       20,000
Derivative liability | AVTX-501        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Initial valuation of warrant liability   3,800   $ 3,500
Derivative liability | AVTX-501 | Measurement Input, Probability Of Success        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Derivative liability, measurement input       0.23
Derivative liability | AVTX-501 | Expected term (in years)        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Derivative liability, measurement input, term       3 years 7 months 6 days
Derivative liability | AVTX-007        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Initial valuation of warrant liability   1,900   $ 1,300
Derivative liability | AVTX-007 | Measurement Input, Probability Of Success        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Derivative liability, measurement input       0.17
Derivative liability | AVTX-007 | Expected term (in years)        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Derivative liability, measurement input, term       4 years 7 months 6 days
Derivative liability | AVTX-007 | Measurement Input, Sales Forecast Peak        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Derivative liability, measurement input       300,000
Derivative liability | AVTX-501 And AVTX-007        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Initial valuation of warrant liability   $ 5,700   $ 4,800
ES | Derivative liability        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Initial valuation of warrant liability       $ 5,000
Warrant liability        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Initial valuation of warrant liability 194,900      
Proceeds from issuance of warrants $ 115,600      
Warrant liability | Private Placement        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Sale of stock (in shares) | shares 11,967,526      
Series C Preferred Stock | Private Placement        
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]        
Sale of stock (in shares) | shares 19,946