Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies (Details)

Commitments and Contingencies (Details)			1 Months Ended	3 Months Ended		12 Months Ended
Commitments and Contingencies (Details)	Mar. 28, 2024 USD ($)	Oct. 27, 2023 USD ($)	Jul. 31, 2019 USD ($)	Mar. 31, 2024 USD ($)	Mar. 31, 2020 USD ($) milestone	Dec. 31, 2018 unit $ / shares	Dec. 31, 2023 USD ($)	Aug. 14, 2023 USD ($)	Jun. 22, 2021 USD ($)	Jun. 09, 2021 USD ($)	May 28, 2021 USD ($)	Mar. 25, 2021 USD ($)	Feb. 03, 2020 USD ($)
Other Commitments [Line Items]
Accrued expenses and other current liabilities				$ 7,383,000			$ 4,172,000
Contingent consideration				12,500,000			0
Payment received			$ 2,000,000
Period after public launch to terminate agreement			3 years
Percentage of net present value of royalty payments			75.00%
Aevi
Other Commitments [Line Items]
Milestone payment				0
AlmataBio Transaction
Other Commitments [Line Items]
Payments to acquire productive assets	$ 7,500,000			7,500,000
Milestone payment due upon first patient dosed in a Phase 2 trial				5,000,000
Aevi
Other Commitments [Line Items]
Number of milestones \| milestone					2
Milestone payment due upon first patient dosed in a Phase 2 trial					$ 6,500,000
Milestone One \| AlmataBio Transaction
Other Commitments [Line Items]
Milestone payment due upon first patient dosed in a Phase 2 trial	5,000,000
Milestone One \| Aevi
Other Commitments [Line Items]
Milestone payment due upon first patient dosed in a Phase 2 trial													$ 2,000,000
Milestone One \| AVTX-009
Other Commitments [Line Items]
Contingent consideration				7,500,000
Milestone Two \| AlmataBio Transaction
Other Commitments [Line Items]
Milestone payment due upon first patient dosed in a Phase 2 trial	$ 15,000,000
Milestone Two \| Aevi
Other Commitments [Line Items]
Milestone payment due upon first patient dosed in a Phase 2 trial													$ 4,500,000
Milestone Two \| AVTX-009
Other Commitments [Line Items]
Contingent consideration				5,000,000
Lilly License Agreement \| AVTX-009 Lilly License Agreement
Other Commitments [Line Items]
Milestone payments				70,000,000
Lilly License Agreement \| AVTX-009 Lilly License Agreement \| Milestone One
Other Commitments [Line Items]
Maximum aggregate milestone payment				720,000,000
Kyowa Kirin Co., Ltd. (KKC) \| AVTX-002 KKC License Agreement
Other Commitments [Line Items]
Upfront license fee												$ 10,000,000
Percent of payments received from sublicensing												30.00%
Research and development expense				0
Cumulative expense recognized to date				0
Kyowa Kirin Co., Ltd. (KKC) \| AVTX-002 KKC License Agreement \| Milestone One
Other Commitments [Line Items]
Maximum aggregate milestone payment												$ 112,500,000
Kyowa Kirin Co., Ltd. (KKC) \| AVTX-002 KKC License Agreement \| Milestone Two
Other Commitments [Line Items]
Maximum aggregate milestone payment												$ 75,000,000
Sanford Burnham Prebys Medical Discovery Institute \| AVTX-008 Sanford Burnham Prebys License Agreement
Other Commitments [Line Items]
Upfront license fee									$ 400,000
Research and development expense				0
Cumulative expense recognized to date				0
Patent costs									500,000
Sanford Burnham Prebys Medical Discovery Institute \| AVTX-008 Sanford Burnham Prebys License Agreement \| Milestone One
Other Commitments [Line Items]
Maximum aggregate milestone payment									24,200,000
Sanford Burnham Prebys Medical Discovery Institute \| AVTX-008 Sanford Burnham Prebys License Agreement \| Milestone Two
Other Commitments [Line Items]
Maximum aggregate milestone payment									$ 50,000,000
Astellas Pharma, Inc. (Astellas) \| AVTX-006 Astellas License Agreement
Other Commitments [Line Items]
Maximum aggregate milestone payment				5,500,000
Upfront license fee				500,000
Research and development expense				0
Cumulative expense recognized to date				500,000
ES \| AVTX-406 License Assignment
Other Commitments [Line Items]
Revenue recognized from milestones to date				0
ES \| Milestone One \| AVTX-406 License Assignment
Other Commitments [Line Items]
Maximum proceeds from milestones										$ 6,000,000
ES \| Milestone Two \| AVTX-406 License Assignment
Other Commitments [Line Items]
Maximum proceeds from milestones										$ 20,000,000
Alto \| AVTX-301 Out-License
Other Commitments [Line Items]
Maximum proceeds from milestones											$ 18,600,000
Revenue recognized from milestones to date				0
AUG Therapeutics, LLC \| Purchase Agreement \| AVTX-800 Series Asset Sale
Other Commitments [Line Items]
Upfront payment paid		$ 200,000
Asset acquisition consideration transferred, liabilities		$ 400,000
Contingent milestone upfront payment percentage		0.20
Contingent milestone payment		$ 15,000,000
Maximum potential payments		$ 45,000,000
TRIS Pharma \| Karbinal Agreement
Other Commitments [Line Items]
Minimum quantity required \| unit						70,000
Make whole payment per unit (in dollars per share) \| $ / shares						$ 30
Apollo AP43 Limited
Other Commitments [Line Items]
Payments for legal settlements				$ 200,000
Accrued expenses and other current liabilities							$ 200,000
Apollo AP43 Limited \| Maximum
Other Commitments [Line Items]
Estimate of possible loss								$ 800,000