Quarterly report pursuant to Section 13 or 15(d)

Cover
- Document and Entity Information
Financial Statements
Notes to Financial Statements
Accounting Policies
- Significant Accounting Policies (Policies)
Notes Tables
Notes Details

Stock Based Compensation - 2016 Equity Incentive Plan (Details)

v3.5.0.2

Stock Based Compensation - 2016 Equity Incentive Plan (Details)		3 Months Ended		9 Months Ended
	May 18, 2016 item shares	Sep. 30, 2016 USD ($) $ / shares shares	Sep. 30, 2015 USD ($)	Sep. 30, 2016 USD ($) $ / shares shares	Sep. 30, 2015 USD ($)
Total stock-based compensation \| $		$ 287,774	$ 29,015	$ 1,439,194	$ 321,228
Option Activity, Number of shares
Balance, beginning of period				959,188
Granted				869,253
Balance, end of period		1,828,441		1,828,441
Vested or expected to vest		1,828,441		1,828,441
Exercisable		657,099		657,099
Option Activity, Weighted-average exercise price
Beginning of period \| $ / shares				$ 7.68
Granted \| $ / shares				3.48
End of period \| $ / shares		$ 5.68		5.68
Vested or expected to vest \| $ / shares		5.68		5.68
Exercisable \| $ / shares		$ 8.19		$ 8.19
Option Activity, Fair value of options granted
Granted \| $		$ 2,124,922		$ 2,124,922
Option Activity, Weighted-average remaining contractual term (in years)
Balance				8 years 6 months 15 days
Vested or expected to vest				8 years 6 months 15 days
Exercisable				7 years 1 month 6 days
Research and development expense
Total stock-based compensation \| $		43,861	13,986	$ 95,013	57,353
General and administrative
Total stock-based compensation \| $		$ 243,913	$ 15,029	1,344,181	$ 263,875
General and administrative \| Chief Executive Officer
Total stock-based compensation \| $				$ 781,266
2011 stock incentive plan
Number of grants to be made under Plan \| item	0
2015 Plan
Number of grants to be made under Plan \| item	0
Common stock remaining for future issuance (in shares)	464,476
2016 Plan
Increase in number of shares reserved for issuance	600,000
Common stock remaining for future issuance (in shares)		691,987		691,987
Annual share reserve increase (as a percent)	4.00%

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The number of grants that will be made under the Plan.

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The percent, applied to total number of outstanding shares of common stock on the last trading day in December of the prior year, by which the share reserve automatically increases on the first day of January of each succeeding calendar year during the term of the Plan.

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Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

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Gross number of share options (or share units) granted during the period.

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Number of options outstanding, including both vested and non-vested options.

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As of the balance sheet date, the weighted-average exercise price for outstanding stock options that are fully vested or expected to vest.

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Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for fully vested and expected to vest options that are exercisable or convertible, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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